1) The golden rule: Start low, go slow

If you remember one dosing principle, make it this: use the smallest amount that gets you the benefit you’re looking for—then increase gradually only if needed.

Why it matters:

• Everyone metabolizes cannabinoids differently (body chemistry, tolerance, diet, sleep, stress, and medications all play a role).

• Some products take longer to kick in than you’d expect—especially edibles—which can tempt people to “stack” doses too quickly. The CDC notes edible effects can take 30 minutes to 2 hours to be felt, and that delay is a common reason people take too much.

Cannabidiol (CBD) is one of the most common cannabinoids found in cannabis. Unlike THC, CBD doesn’t create the “high” feeling most people associate with marijuana.

Instead, CBD is often used by patients who want a more functional, daytime-friendly experience—or who want a “buffer” alongside THC (especially in balanced ratio products like 1:1 THC:CBD).